发明名称 |
Polymer-modified synthetic proteins |
摘要 |
The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG. 1D), and of pharmaceutical compositions that contain such proteins.
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申请公布号 |
US2004115774(A1) |
申请公布日期 |
2004.06.17 |
申请号 |
US20030332385 |
申请日期 |
2003.01.08 |
申请人 |
KOCHENDOERFER GERD G;BOTTI PAOLO;BRADBURNE JAMES A;CHEN SHIAH-YUN;CRESSMAN SONYA;HUNTER CHRISTIE L;KENT STEPHEN B H;LOW DONALD W;WILKEN JILL G |
发明人 |
KOCHENDOERFER GERD G;BOTTI PAOLO;BRADBURNE JAMES A;CHEN SHIAH-YUN;CRESSMAN SONYA;HUNTER CHRISTIE L;KENT STEPHEN B H;LOW DONALD W;WILKEN JILL G |
分类号 |
C07K1/107;C07K14/52;C12P21/02;(IPC1-7):C07K14/54;C07H21/04 |
主分类号 |
C07K1/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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