发明名称 THERAPEUTIC USE OF MEDICINE TO ADJUST ALPHA SMOOTH MUSCLE ACTIN ACTIVITY
摘要 <P>PROBLEM TO BE SOLVED: To enable cure of ligament injury, osteoporosis and healing of wound, and to perform tissue engineering, medicine delivery, and prevention of tumor cell metastasis. <P>SOLUTION: A method executed is: preparing a ground substance/cell combination to repair injured musculoskeletal tissue of a patient. The ground substance/cell combination is to be transplanted to the position of injured musculoskeletal tissue. The method comprises a step to breed a musculoskeletal cell or a marrow interstitium stem cell taken from a patient on the ground substance. The step is executed by bringing the cell into contact with a medicine in sufficient concentration to obstruct or promote the in vitro generation of alpha smooth muscle actin (SMA) or biological activity. <P>COPYRIGHT: (C)2004,JPO
申请公布号 JP2004167270(A) 申请公布日期 2004.06.17
申请号 JP20040031986 申请日期 2004.02.09
申请人 BRIGHAM & WOMEN'S HOSPITAL INC 发明人 SPECTOR MYRON
分类号 C12N5/06;A61K38/18;A61K38/21;A61K38/22;A61K38/27;A61K45/00;A61L27/00;A61L27/22;A61L27/38;A61P17/02;A61P19/08;A61P19/10;A61P21/00;A61P35/04;A61P43/00 主分类号 C12N5/06
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