发明名称 |
PREVENTION OF PRIMARY SJÖGREN'S SYNDROME BY ICA69 DEFICIENCY |
摘要 |
This invention relates to identificatican of an autoantigen implicated in the development and progression of Sjögren's Syndrome (pSS); particularly to the disease modifying effect of creating a deficiency in the ICA69 autoantigen; and most particularly to development of diagnostic and therapeutic avenues, means for the differential diagnosis of pSS versus other autoimmune disease, e.g. Systemic lupus erythematosis (SLE), and procedures for immunotherapeutic treatment effective to alter the course and progression of pSS. |
申请公布号 |
WO2004031767(A3) |
申请公布日期 |
2004.06.17 |
申请号 |
WO2003CA01535 |
申请日期 |
2003.10.03 |
申请人 |
THE HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE |
发明人 |
DOSCH, HANS-MICHAEL;WINER, SHAWN |
分类号 |
A01K67/027;A61K39/00;A61K39/395;C12N15/85;G01N33/53;G01N33/564 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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