摘要 |
This invention relates to indolizine compounds having formula in which R1 is H, lower alkyl, lower alkoxy, OH, F, Cl, Br, I, NO2, or CN; R2 is alkyl optionally substituted with lower alkoxy, OH, CN, F, Cl, Br, I, NO2, NH2, C(O)NH2, CO2H, or CO2R'; or aryl optionally substituted with lower alkyl, lower alkoxy, OH, CN, F, Cl, Br, I, NO2, NH2, or C(O)NH2, CO2H, or CO2R'; R3 is H or lower alkyl; R4 is N-oxy pyridyl or pyridyl optionally substituted with F, Cl, Br, or I; and X is C(R'R''), N(R'), O, S, S(O), S(O)2, C(O), C(O)-N(R'), N(R')-C(O), or deleted. Each of R' and R'', independently, is H, or alkyl optionally substituted with lower alkoxy, OH, CN, F, Cl, Br, I, NO2, NH2, or C(O)NH2.
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