发明名称 |
SUBSTITUTED UREAS AND CARBAMATES |
摘要 |
The invention provides compounds of formula I: useful in treating Alzheimer~ s disease and other similar diseases. These compounds include inhibitors of th e beta-secretase enzyme that are useful in the treatment of Alzheimer~s diseas e and other diseases characterized by deposition of A beta peptide in a mammal . The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
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申请公布号 |
CA2507484(A1) |
申请公布日期 |
2004.06.17 |
申请号 |
CA20032507484 |
申请日期 |
2003.11.26 |
申请人 |
PHARMACIA & UPJOHN COMPANY LLC;ELAN PHARMACEUTICALS, INC. |
发明人 |
TUCKER, JOHN A.;PULLEY, SHON R. |
分类号 |
A61P25/28;C07C271/20;C07C271/52;C07C275/24;C07C275/28;C07D213/40;C07D215/42;C07D277/28;C07D309/14;C07D311/68;C07D311/76;C07D317/72;C07D335/06;C07D405/04;C07D407/06;(IPC1-7):C07C271/20;C07C311/05;A61K31/17;C07C275/26;A61K31/325;A61K31/353;A61K31/63 |
主分类号 |
A61P25/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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