METHOD AND DEVICE FOR TRANSPORTING OR BINDING-SPECIFIC SEPARATION OF ELECTRICALLY CHARGED MOLECULES

摘要

Electrically charged molecules need to be transported in order to create a D NA sensor. According to the invention, the following measures are undertaken: base metals are introduced into a solution as a positive ion; negatively charged molecules are transported in an opposite direction and are enriched in the vicinity of the measuring electrodes. Binding-specific separation of the charged molecules can be achieved by forming metal layers on the measuring electrodes by depositing metal ions from the solution when a suitable potential is selected. Target DNA can more particularly be introduced into t he vicinity of catcher molecules on the measuring electrodes and non-specifical ly bound DNA can be removed. According to the associated device, the electrode arrangement (20,30) is associated with a sacrificial electrode (40) made of a more base metal than the material of the measuring electrodes (20,30). The measuring electrodes (20,30) in particular are made of noble metal, preferab ly gold, and the sacrificial electrode (40) is made of copper.