PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED beta -AMINO NITRILES THROUGH THE RING OPENING OF AZIRIDINES

摘要

The present invention comprises the simultaneous ring opening and concomitan N-substitution of various N-tosyl aziridines with different aliphatic and aromatic nitriles in presence of catalytic amount of metal triflates to afford different N-substituted beta -amino nitriles in excellent yields and selectivities.