发明名称 TREATMENT OF MULTIPLE SCLEROSIS WITH BRAIN TARGETED ANTI OXIDANT COMPOUNDS
摘要 A method of treating multiple sclerosis, the method comprises administering to a subject in need thereof a therapeutically effective amount of a compound, the compound having: (a) a combination of molecular weight and membrane miscibility properties for permitting the compound to cross the blood brain barrier of the organism; (b) a readily oxidizable chemical group for exerting antioxidation properties; and (c) a chemical make-up for permitting the compound or its intracellular derivative to accumulate within the cytoplasm of cells.
申请公布号 WO2004012652(A9) 申请公布日期 2004.06.17
申请号 WO2003IL00635 申请日期 2003.07.31
申请人 YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;MOR RESEARCH APPLICATIONS LTD.;RAMOT AT TEL AVIV UNIVERSITY LTD.;ATLAS, DAPHNE;MELAMED, ELDAD;OFFEN, DANIEL 发明人 ATLAS, DAPHNE;MELAMED, ELDAD;OFFEN, DANIEL
分类号 A61K31/00;(IPC1-7):A61K31/225;A61K31/22;A61K31/195 主分类号 A61K31/00
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