| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a plasmid usable for genetically modifying bacteria having Gram-positive dye-affinity, especially, industrially and medically important lactobacillus. <P>SOLUTION: The bacterial vector plasmid has an efficient replication origin in Gram-positive bacteria. The plasmid has at least one marker gene which expresses itself in a bacterial host strain, an efficient replication system which is thermosensitive based on a temperature compatible with the viability of the host strain, and the temperature of replication inhibition below or equal to approximately 37°C. <P>COPYRIGHT: (C)2004,JPO |
