发明名称 |
PROCESS FOR SYNTHESIS BIS-ARYL DIAMIDOXIME COMPOUNDS |
摘要 |
Bis-aryl diamidoxime compounds, such as 2,5-bis [4-hydroxy and 4-O-alkylamidinophenyl] furans, can be prepared from 2,5-bis tri-alkylstannanes via a one step palladium-catalyzed cross reaction. Bis-aryl diamidoxime compounds, such as 2,5-bis [4-hydroxy and 4-0-alkylamidinophenyl] furans, are useful as therapeutic compounds. The disclosed process is scalable, simpler, more economic and more feasible than other presently known methods of preparing 2,5-bis [4-hydroxy and 4-O-alkylamidinophenyl] furans and other bis-aryl diamidoxime compounds. |
申请公布号 |
WO2004051217(A2) |
申请公布日期 |
2004.06.17 |
申请号 |
WO2003US37788 |
申请日期 |
2003.11.25 |
申请人 |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.;BOYKIN, DAVID, W.;ANBAZHAGAN, MARIAPPAN;TIDWELL, RICHARD, R. |
发明人 |
BOYKIN, DAVID, W.;ANBAZHAGAN, MARIAPPAN;TIDWELL, RICHARD, R. |
分类号 |
C07C249/00;C07D207/46;C07D307/02;C07D333/12;C07D405/00;G01N |
主分类号 |
C07C249/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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