The present invention provides methods and compositions for the treatment of DNA damage related disorders. One embodiment of the invention is a prophylactic method for the prevention of cancer using a chloroquine compound. Another embodiment is a method for the inhibition of side effects associated with chemotherapeutic and radiotherapeutic agents using chloroquine compounds.
申请公布号
WO2004050837(A2)
申请公布日期
2004.06.17
申请号
WO2003US37838
申请日期
2003.11.26
申请人
ST. JUDE CHILDREN'S RESEARCH HOSPITAL;KASTAN, MICHAEL, B.;BAKKENIST, CHRISTOPHER, J.