发明名称 |
Universal reagent for isotopically tagging peptides |
摘要 |
<p>Compounds, compositions, methods for sequencing proteins and peptides, and methods for identifying proteins and peptides in a mixture, are disclosed. Compounds of formula A-B-C wherein A is a nucleophilic reactive group, B is a detectable moiety capable of being isotopically labeled, and C is a charge replacement group, are used to label the peptides at the N-terminus or the C-terminus. The tagged peptides can then be analyzed by mass spectroscopy. <IMAGE></p> |
申请公布号 |
EP1429147(A1) |
申请公布日期 |
2004.06.16 |
申请号 |
EP20030257854 |
申请日期 |
2003.12.15 |
申请人 |
AGILENT TECHNOLOGIES, INC. |
发明人 |
ROBOTTI, KARLA M.;APFFEL, JAMES ALEXANDER JR. |
分类号 |
C07D401/14;C07D403/12;G01N33/50;G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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