Certain variants of Lipolase (wild-type Humicola lanuginosa lipase) have a particularly good first-wash performance in a detergent solution. The variants should comprise one or more substitutions with positive amino acids near the N-terminal in the three-dimensional structure. The variants should further comprise a peptide addition at the C-terminal and/or should meet certain limitations on electrically charged amino acids at positions 90-101 and 210.
申请公布号
EP1428874(A2)
申请公布日期
2004.06.16
申请号
EP20030024829
申请日期
2000.03.30
申请人
NOVOZYMES A/S
发明人
VIND, JESPER;SVENDSEN, ALLAN;PATKAR, SHAMKANT, A.;ANDERSEN, KIM, V.;HALKIER, DORTE, A.;BOJSEN, KIRSTEN