发明名称 The title is not available
摘要 <p>Triazine derivatives of the formula (I) and physiologically acceptable salts and solvates thereof, in which R1, R2, A and R5 are as defined in Claim 1, exhibit phosphodiesterase IV inhibition and can be employed for the treatment of allergic diseases, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin diseases, inflammatory diseases, autoimmune diseases, such as, for example, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumour growth or tumour metastases, sepsis, memory disorders, atherosclerosis and AIDS, furthermore for inhibiting the formation of TNFalpha.</p>
申请公布号 CZ20040213(A3) 申请公布日期 2004.06.16
申请号 CZ20040000213 申请日期 2002.06.19
申请人 MERCK PATENT GMBH 发明人 EGGENWEILER HANS-MICHAEL;WOLF MICHAEL;BEIER NORBERT;LEIBROCK JOACHIM;SCHELLING PIERRE;GASSEN MICHAEL;EHRING THOMAS
分类号 C07D253/06;A61K31/53;A61P1/04;A61P3/10;A61P7/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P35/04;A61P37/00;A61P37/06;A61P37/08;A61P43/00;C07D253/075;C07D401/12;(IPC1-7):C07D243/06 主分类号 C07D253/06
代理机构 代理人
主权项
地址