发明名称 |
Methods and compositions for inhibition of membrane fusion-associated events, including HIV transmission |
摘要 |
The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.
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申请公布号 |
US6750008(B1) |
申请公布日期 |
2004.06.15 |
申请号 |
US19990350841 |
申请日期 |
1999.07.09 |
申请人 |
TRIMERIS, INC. |
发明人 |
JEFFS PETER;LACKEY JOHN WILLIAM;ERICKSON JOEL BURTON;LAWLESS MARY KATHERINE;MERUTKA GENE |
分类号 |
G01N33/50;A61K38/16;A61K45/00;A61P31/18;C07K14/02;C07K14/055;C07K14/11;C07K14/115;C07K14/12;C07K14/125;C07K14/13;C07K14/135;C07K14/155;C07K14/16;G01N33/15;G01N33/566;G01N33/569;G01N33/68;(IPC1-7):C12Q1/70 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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