发明名称 |
Diimino compounds for use as modulators of cell regulation |
摘要 |
Compositions, methods of use, isolation and biosynthesis of diimino-piperazine derivatives useful for the modification of sphingolipid metabolism and other biological functions are described. The preferred derivative is 2,6-bis-(omega-aminobutyl)-3,5-diimino-piperazine. This is a naturally occurring biochemical compound isolated from cells. The diimino-piperazine derivatives are useful as therapeutic agents when administered to patients to treat diseases and disorders involving cell regulation.
|
申请公布号 |
US6750211(B2) |
申请公布日期 |
2004.06.15 |
申请号 |
US20030357297 |
申请日期 |
2003.02.03 |
申请人 |
EMORY UNIVERSITY |
发明人 |
MERRILL, JR. ALFRED H.;WARDEN LISA;LIOTTA DENNIS C. |
分类号 |
A61K31/495;A61K31/496;C07D241/06;(IPC1-7):A61K31/33;A61K31/434;A61K31/44;C07D213/00;C07D211/70 |
主分类号 |
A61K31/495 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|