发明名称 |
A PROCESS FOR THE PREPARATION OF 1-[[3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE-5-YL)-4-ETHOXYPHENYL]SULFONYL]-4-METHYLPIPERAZINE AND INTERMEDIARY COMPOUNDS |
摘要 |
A process is provided for the preparation of a compound of formula (IA) (sidenafil/ViagraTM) comprising reacting a compound of formula (IIA) in the presence of -OR, wherein R in the case of formation of compound (IA) is cì2cì3 where X is a leaving group , (IA) (IIA). |
申请公布号 |
UA66787(C2) |
申请公布日期 |
2004.06.15 |
申请号 |
UA19990105491 |
申请日期 |
1999.10.08 |
申请人 |
PFIZER RESEARCH AND DEVELOPMENT COMPANY N.V./S.A. |
发明人 |
DANN PETER JAMES;LEVETT PHILIPPE CHARLES |
分类号 |
C07D295/22;A61K31/519;A61P15/10;C07D231/40;C07D231/54;C07D295/26;C07D401/02;C07D401/06;C07D487/00;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
C07D295/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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