IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

摘要

An imidazole derivative represented by the formula (I): (I) wherein R represents an optionally substituted cyclic hydrocarbon group or optionally substituted heterocyclic group; W represents a bond or optionally substituted divalent chain hydrocarbon group; X represents an optionally substituted divalent hydrocarbon group; Y represents -CO-, -S(O)-, -S(O)2-, or a bond; ring A represents an optionally substituted pyrrolidine ring, optionally substituted piperidine ring, or optionally substituted perhydroazepine ring; Z<1> and Z<3> each independently represents a bond or optionally substituted divalent chain hydrocarbon group; Z<2> represents -N(R<1>)-, -O-, -S(O)-, -S(O)2-, -CO-, -CH(R<1>)-, or a bond; ring B represents an optionally substituted imidazole ring, provided that a substituent of the imidazole ring represented by B may be bonded to R<1> to form an optionally substituted ring; and a is 0, 1, or 2. The imidazole derivative is useful as a therapeutic agent for thrombosis.