发明名称 |
IRON SEQUESTRATION OR ELIMINATION TO REDUCE NEURODEGENERATION OR PARKINSONS DISEASE PROGRESSION |
摘要 |
This invention pertains to the discovery that elevated level of free iron causal in the onset and/or progression of diseases characterized by neural degeneration (e.g., Parkinson's Disease). It was also discovered that lowering free iron levels can inhibit (e.g. reduce or eliminate) the onset and/or progression of one or more symptoms of such diseases. Thus, in one embodiment this invention provides a method of inhibiting neural degeneration in a mammal. The method involves reducing free iron levels in a neural tissue of said animal in an amount sufficient to inhibit neural degeneration in said neural tissue. |
申请公布号 |
WO2004006856(A3) |
申请公布日期 |
2004.06.10 |
申请号 |
WO2003US22112 |
申请日期 |
2003.07.11 |
申请人 |
THE BUCK INSTITUTE FOR RESEARCH ON AGING;ANDERSEN, JULIE, K. |
发明人 |
ANDERSEN, JULIE, K. |
分类号 |
A61K31/195;A61K31/47;A61K38/40 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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