MAPCAXS AS MODIFIERS OF THE APC AND AXIN PATHWAYS AND METHODS OF USE
摘要
Human MAPCAX genes are identified as modulators of the APC and Axin pathway, and thus are therapeutic targets for disorders associated with defective APC and Axin function. Methods for identifying modulators of APC and Axin, comprising screening for agents that modulate the activity of MAPCAX are provided.
申请公布号
WO2004048539(A2)
申请公布日期
2004.06.10
申请号
WO2003US37546
申请日期
2003.11.24
申请人
EXELIXIS, INC.;GENDREAU, STEVEN, BRIAN;MORABLANCO, EVA, LORENA;BJERKE, LYNN, MARGARET
发明人
GENDREAU, STEVEN, BRIAN;MORABLANCO, EVA, LORENA;BJERKE, LYNN, MARGARET