| 摘要 |
The application discloses Sz. pombe yeast cells which have been modified so that a F-Protein Coupled Receptor (GPCR)-regulated signalling pathway is derepressed during the mitotic phase of cell growth. Isolated nucleic acid molecules encoding constructs used to make the yeast cells, uses of the cells and nucleic acid molecules to study GPCR pathways and to isolate compounds which effect in such pathways are also disclosed.
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