| 摘要 |
The present invention provides a method for assaying an ability to control the neurocyte plasticity which is dependent on a transcription regulatory factor comprising any of the amino acid sequences selected for example from the amino acid sequence group consisting of the amino acid sequences represented by SEQ ID Nos.1 to 3 comprising the steps: (1) a first step for bringing a test substance into contact with a mammalian cell expressing the transcription regulatory factor; and, (2) a second step, after the first step, for measuring the expression level of a marker protein gene present on the transcription regulatory factor-dependent neurocyte plasticising pathway in the mammalian cell or an index value correlating with the level; and, (3) a step for evaluating the ability possessed by the test substance based on the expression level or the index value correlating with the level measured in the second step, and the like.
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