发明名称 |
Methods and systems for identifying putative fusion transcripts, polypeptides encoded therefrom and polynucleotide sequences related thereto and methods and kits utilizing same |
摘要 |
The present invention provides a method of identifying putative fusion transcripts. The method comprises: (a) computationally aligning a first database of annotated polynucleotide sequences with a second database of expressed polynucleotide sequences; and (b) identifying in the second database an expressed polynucleotide sequence complementary to at least two non-contiguous sequences of the first database, the at least two non-contiguous sequences being selected from the group consisting of non-homologous polynucleotide sequences mapped to different chromosomes, polynucleotide sequences mapped to different loci of a single chromosome and polynucleotide sequences mapped to a single locus and not being a part of a splice isoform, the expressed polynucleotide sequence identified being a putative fusion transcript.
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申请公布号 |
US2004110227(A1) |
申请公布日期 |
2004.06.10 |
申请号 |
US20030391530 |
申请日期 |
2003.03.19 |
申请人 |
LEVANON EREZ;TOPORIK AMIR;AKIVA PINI |
发明人 |
LEVANON EREZ;TOPORIK AMIR;AKIVA PINI |
分类号 |
G01N33/48;G01N33/50;G01N33/53;G06F19/00;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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