A compensating drug delivery system is described. A drug-containing reservoir (10) is connected to a needle array (45) through a flow tube (11). Delivery through this flow tube is regulated by a metering means, a valving means (14) and a microprocessor (17), and inaccuracies in delivery rate are compensated. Additionally, systems and methods for measuring the flow of a liquid along a conduit a heat source (13) and an optical sensing means (16). An optical sensing means comprising a light source (36) illuminating the liquid in the conduit downstream from the heat source and an optical detector (38) sensing the change in an optical property in the portion of liquid that is heated by the heat source. The liquid velocity is calculated by the time required for the heated portion to move from the thermal application point to the optical sensing point and the distance between the two points.
申请公布号
WO03097120(B1)
申请公布日期
2004.06.10
申请号
WO2002US38822
申请日期
2002.12.04
申请人
THERAFUSE, INC.;SAGE, BURTON, H., JR.;CATANZARO, BRIAN, E.