发明名称 |
MODULATORS OF P-SELECTIN GLYCOPROTEIN LIGAND 1 |
摘要 |
Compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as autoimmune diseases, transplant rejection, and allergic diseases.
|
申请公布号 |
WO03013603(A8) |
申请公布日期 |
2004.06.10 |
申请号 |
WO2002US07498 |
申请日期 |
2002.03.13 |
申请人 |
ABGENOMICS CO.;RONG-HWA, LIN;CHUNG-HSIUN, WU;PEI-LING, HSU |
发明人 |
RONG-HWA, LIN;CHUNG-HSIUN, WU;PEI-LING, HSU |
分类号 |
G01N33/48;A61K39/395;A61K45/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07K16/28;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/577;(IPC1-7):A61K39/395 |
主分类号 |
G01N33/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|