发明名称 |
EFFICIENT METHOD FOR PRODUCING COMPOSITIONS ENRICHED IN TOTAL PHENOLS |
摘要 |
This invention provides a process for the preparation of compositions enrich ed in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This inventio n also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth i n Figures 10-13. This invention encompasses methods of using the total phenol- enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes virus es such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.
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申请公布号 |
CA2506651(A1) |
申请公布日期 |
2004.06.10 |
申请号 |
CA20032506651 |
申请日期 |
2003.11.21 |
申请人 |
PHENOLICS, LLC |
发明人 |
NICHOLS, REBECCA;DAUGHERTY, F. JOSEPH;GOURDIN, GERALD T.;TEMPESTA, MICHAEL S.;RICHHEIMER, STEVEN L.;BAILEY, DAVID T.;FREEBERG, DELANO R. |
分类号 |
A61K31/352;A61K31/70;A61K36/185;A61K36/35;A61K36/45;A61K36/73;A61K36/736;A61K36/87;C07D311/62;(IPC1-7):A61K31/704;A61K47/00;A61K35/78 |
主分类号 |
A61K31/352 |
代理机构 |
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