摘要 |
This invention relates to a tamper-resistant transdermal-delivery device comprising an opioid, or a pharmaceutically acceptable salt thereof, and an acyl opiod antagonist, or a pharmaceutically acceptable salt thereof. The transdermal-delivery device allows an analgesically effective amount of the opioid, or a pharmaceutically acceptable salt thereof, to be transdermally administered to a patient. The invention further relates to methods for treating or preventing pain in a patient comprising contacting the skin of a patient in need thereof with the transdermal-delivery device of the invention for an amount of time sufficient to treat or prevent pain. The invention further relates to acyl opioid antagonists.
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申请人 |
EURO-CELTIQUE, S.A.;SHEVCHUK, IHOR;CASSIDY, JAMES, P.;REIDENBERG, BRUCE;SHARP, DALE, E.;KUPPER, ROBERT, J. |
发明人 |
SHEVCHUK, IHOR;CASSIDY, JAMES, P.;REIDENBERG, BRUCE;SHARP, DALE, E.;KUPPER, ROBERT, J. |