发明名称 |
DENDRIMER CONJUGATES FOR SELECTIVE OF PROTEIN AGGREGATES |
摘要 |
<p>Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates are effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.</p> |
申请公布号 |
WO2004047869(A1) |
申请公布日期 |
2004.06.10 |
申请号 |
WO2003DK00812 |
申请日期 |
2003.11.26 |
申请人 |
DANMARKS FOEDEVARE- OG VETERINAERFORSKNING;HEEGAARD, PETER;BOAS, ULRIK |
发明人 |
HEEGAARD, PETER;BOAS, ULRIK |
分类号 |
A61K47/48;(IPC1-7):A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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