发明名称 |
MEDICINAL USE OF HISTONE DEACETYLASE INHIBITOR AND METHOD OF EVALUATING ANTITUMOR EFFECT THEREOF |
摘要 |
A therapeutic agent for prostate cancer and malignant lymphoma containing FK228 or a salt thereof as an active ingredient, and a method for evaluating an antitumor effect of a histone deacetylase inhibitor which includes at least a step of treating a test cell with a histone deacetylase inhibitor, a step of measuring change in the expression amount of a specific gene in the test cell before and, after the treatment with the inhibitor, comparing the both expression amounts.
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申请公布号 |
EP1426054(A1) |
申请公布日期 |
2004.06.09 |
申请号 |
EP20020760663 |
申请日期 |
2002.08.20 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
SASAKAWA, YUKA;NAOE, YOSHINORI |
分类号 |
A61K38/12;A61K38/15;A61P13/08;A61P35/00;A61P43/00;C12Q1/34;C12Q1/68;G01N33/50;G01N33/574;(IPC1-7):A61K38/15;C12Q1/02 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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地址 |
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