Anti-tumour pharmaceutical composition comprising N-vanillyl fatty acid amide

摘要

The present invention provides an anti-tumor pharmaceutical composition having a high anti-tumor effect with low side-effects. <??>The anti-tumor pharmaceutical composition comprises a N-vanillyl fatty acid amide of formula (1): <CHEM> wherein -CO-R group represents a saturated or unsaturated fatty acid residue containing from 14 to 32 carbon atoms. <??>According to the invention, there is provided an anti-tumor pharmaceutical composition comprising a N-vanillyl fatty acid amide which is related to capsaicin wherein the composition has a low side-effect and a high anti-tumor effect, in particular an anti-melanoma effect and an anti-leukemia cell effect; and has a very low pungency, a stimulatory and a preinflammatory effect.