TRANSGENIC CLONED COW PRODUCING HUMAN LACTOFERRICIN AND METHOD FOR PRODUCING THE SAME

摘要

PURPOSE: Transgenic cloned cow producing human lactoferricin and a method for producing the same are provided, thereby economically and efficiently producing biological medicines from the cloned animals and easily obtaining human lactoferricin from the milk of cloned animals. CONSTITUTION: The method for producing the transgenic cloned cow producing human lactoferricin comprises the steps of: (a) preparing nucleus donor cells by transferring a gene encoding human lactoferricin to somatic cell lines collected from cow; (b) preparing matured nucleus recipient ova collected from cow by removing oocytes from nucleus recipient ova of cow and removing cytoplasm including the first polar body; and (c) transferring the nucleus donor cells to the matured nucleus recipient ova and fusing them, wherein the somatic cells are collected from matured cow; and the nucleus transplanted ovum is SNU-B2(KCTC 10355BP).