| 摘要 |
PROBLEM TO BE SOLVED: To provide a new method for evaluating aβcell dysfunction improving agent, such as an insulin-resistant therapeutic agent and an insulin secretion promoting agent, by finding out a gene useful as an indicator of a symptom of diabetes and improvement thereof, especially, improvement of theβcell dysfunction, and utilizing the gene or a product of the gene, and to provide a new method for evaluating theβcell dysfunction of an examinee. SOLUTION: The method for evaluating theβcell dysfunction improving effect of a test substance by using an expression level of the gene expressed by a specific base sequence or the product of the gene in a specimen under an administration condition of the test substance as the indicator, the method for evaluating theβcell dysfunction of the examinee, a primer for the methods, a kit containing a probe, or the like, are provided, respectively. COPYRIGHT: (C)2004,JPO
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