发明名称 Monovalent-selective cation exchangers as oral sorbent therapy
摘要 The present invention relates to compounds and methods of treating patients exhibiting high levels serum toxins. The present invention finds particularly advantageous use for patients suffering from renal and/or liver dysfunction. The present invention includes administering to such patients a zirconium-silicate sorbent in amounts sufficient to reduce one or more of the levels of the serum toxins. The zirconium-silicate sorbent can function as a cation exchanger and exchange one or more cations and adsorb cationic toxics, such as, ammonium cations, potassium cations, sodium cations, calcium cations, magnesium cations, from the patient. Additionally, the zirconium-silicate sorbent can be combined with one or more of a carbon agent (or charcoal), zinc oxide and/or agent to enhance the intestine permeability such as a non absorbable alcohol.
申请公布号 US2004105895(A1) 申请公布日期 2004.06.03
申请号 US20040467229 申请日期 2004.01.12
申请人 ASH STEPHEN R 发明人 ASH STEPHEN R
分类号 A61K33/00;A61K33/06;A61K33/24;A61K47/48;(IPC1-7):A61K33/24 主分类号 A61K33/00
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