DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLON AS POTASSIUM CHANNEL AND/OR CORTICAL NEURON ACTIVITY MODULATORS

摘要

Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels and/or depressing cortical neuron activity. More particularly, the invention provides derivatives of N-phenylanthranilic acid or 2-benzimidazolone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders and as neuroprotective agents.