IMPROVED HYDROPHILIC MONOLITHIC COLUMNS FOR SEPARATION OF SACCHARIDE MIXTURES
摘要
Polar, monolithic CEC columns having an amine and/or cyano functional stationary phase are used to separate complex mixtures of saccharides. Using the positive-ion mode of detection for neutral saccharides, detection conditions were optimized to low-femtomole sensitivities with the use of an ion trap mass spectrometer. The described column technology provides a universal system for separating a wide range of carbohydrates: mono- and oligosaccharides with the intact reducing end, as well as saccharide alditols.
申请公布号
WO2004045503(A2)
申请公布日期
2004.06.03
申请号
WO2003US34089
申请日期
2003.10.24
申请人
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC.;QUE, AMY, H.;NOVOTNY, MILOS, V.