发明名称 |
Methods and compositions for detecting receptor-ligand interactions in single cells |
摘要 |
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides methods and compositions of screening for bioactive agents capable of coordinately modulating the activity of a plurality of proteins in single cells. The methods and compositions can be used to determine the protein activation profile of a cell for predicting or diagnosing a disease state, and for monitoring treatment of a disease state.
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申请公布号 |
US2004106156(A1) |
申请公布日期 |
2004.06.03 |
申请号 |
US20030346620 |
申请日期 |
2003.01.16 |
申请人 |
PEREZ OMAR D.;NOLAN GARRY P. |
发明人 |
PEREZ OMAR D.;NOLAN GARRY P. |
分类号 |
C12Q1/48;G01N33/50;G01N33/569;G01N33/573;(IPC1-7):G01N33/53;G01N33/567 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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