| 摘要 |
Direct bromination of hydroxy aromatic compounds by electrolysis of mixtures comprising the hydroxy aromatic compound, a source of bromide ion, and an organic solvent provides product brominated hydroxy aromatic compounds at synthetically useful rates with high para-selectivity. The process does not require the use or handling of molecular bromine or bromine complexes and allows the full use of the bromide source without generating hydrogen bromide as a by-product of the reaction. The simple electrochemical equipment required by the present process, for example an undivided electrochemical cell, makes the process less capital intensive than analogous electrochemical processes carried out in divided cells. The use of hydrobromic acid as the source of bromide ion provides clean reaction with nearly exclusive formation of the target brominated product.
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