| 发明名称 |
A CRYSTALLIZATION METHOD FOR PURIFICATION OF CALCIPOTRIENE |
| 摘要 |
<p>Provided is a crystallization method for reducing the level of impurities in calcipotriene in which a solution of a starting calcipotriene in a first process solvent, for example THF, is combined with second process solvent, for example methyl formate, and, after cooling, calcipotriene is isolated. The method can include a slurry step for reducing the level of residual first process solvent.</p> |
| 申请公布号 |
WO2004046097(A1) |
申请公布日期 |
2004.06.03 |
| 申请号 |
WO2003US37138 |
申请日期 |
2003.11.18 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD.;TEVA PHARMACEUTICALS USA, INC.;SCHWARTZ, ANCHEL;MAIMON, ASHER |
发明人 |
SCHWARTZ, ANCHEL;MAIMON, ASHER |
| 分类号 |
C07C401/00;(IPC1-7):C07C401/00 |
主分类号 |
C07C401/00 |
| 代理机构 |
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