| 摘要 |
The present invention relates to a compound of formula (I) wherein each R1 is independently (II), wherein W is an aryl, alkyl or heteroaryl group, each of which may be optionally substituted by one or more of OH, halogen, an isothiocyanate group, a haloacetamide, maleimide, COOH, NO2, NH2, alkyl, haloalkyl, alkoxy, (CO)n(O)mZ, a polyethylene glycol group, an alkyl sulfonate group, an alkyl-COOH group, a substituted or unsubstituted benzyl group, or a sugar derivative; R2 is H, a halogen, an isothiocyanate group, a haloacetamide, maleimide, Y-aryl or Y-heteroaryl, where Y is O, S, NH, C(O) or CO2, and where said aryl or heteroaryl group may be optionally substituted by one or more of: OH, halogen, an isothiocyanate group, a haloacetamide, maleimide, COOH, NO2, NH2, alkyl, haloalkyl, alkoxy, (CO)n'(O)m'Z', a polyethylene glycol group, an alkyl sulfonate group, an alkyl-COOH group, a substituted or unsubstituted benzyl group, or a sugar derivative; Z and Z' are each independently silicon-containing protecting groups and m, m', n and n' are each independently 0 or 1; X is a C1-20 alkylene group, optionally substituted by one or more substituents selected from halogen, NO2, CN, OH, OMe, NH2, CF3, COOH and CONH2; each R3, R4, R5 and R6 is independently H, alkyl, alkoxy, halogen or OH; and M is 2H or a metal. |
