发明名称 PRODUCTS AND PROCESSES FOR MODULATING PEPTIDE-PEPTIDE BINDING DOMAIN INTERACTIONS
摘要 The present invention relates to therapeutic compounds and methods of use of these therapeutic compounds for treating cellular proliferative disorders. The invention also provides three-dimensional structures of a Polo-like kinase and methods for designing or selecting small molecule inhibitors using these structures, and the therapeutic use of such compounds. The invention also includes a method for identifying novel phosphopeptide-binding domains.
申请公布号 WO2004046317(A2) 申请公布日期 2004.06.03
申请号 WO2003US36392 申请日期 2003.11.14
申请人 MASSACHUSETTS INSTITUE OF TECHNOLOGY;YAFFE, MICHAEL, B.;ELIA, ANDREW, E.H.;RELLOS, PETER;CANTLEY, LEWIS, C.;SMERDON, STEPHEN, J.;MANCKE, ISAAC 发明人 YAFFE, MICHAEL, B.;ELIA, ANDREW, E.H.;RELLOS, PETER;CANTLEY, LEWIS, C.;SMERDON, STEPHEN, J.;MANCKE, ISAAC
分类号 A61K38/00;C07K14/47;C12N9/12;C12N15/10;G01N33/53 主分类号 A61K38/00
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