摘要 |
A system and method for measuring ventricular function in an isolated, perfused heart using an intraventricular balloon connected to a plumbing circuit containing a fluid, the plumbing circuit including (a) a valve for selectively opening the plumbing circuit to (i) atmospheric pressure or (ii) a pressure control circuit of a pressure control apparatus or (b) a pressure control apparatus which can be selectively connected to the plumbing circuit, including the steps of establishing a base pressure by (1) opening the valve to atmospheric pressure or the pressure control circuit or (2) operating the pressure control apparatus, after equalization of the pressure within the intraventricular balloon with the base pressure, closing the valve or stopping operation of the pressure control apparatus, following the closing of the valve, measuring ventricular function as a function of a titrated infusion of fluid into the plumbing circuit and intraventricular balloon, performing an intervention, and repeating at least the first three steps.
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