发明名称 IMPROVED STANNOUS ORAL COMPOSITIONS
摘要 The present invention relates to single phase oral compositions comprising a stannous ion source, a fluoride ion source, and a polymeric mineral surface active agent that binds stannous, said compositions providing adequate therapeutic efficacy with minimal side effects of tooth staining and astringency. The composition simultaneously provides reduction and control of supragingival calculus. The present invention also provides a method for effective delivery of stannous-containing compositions with minimal side effects of tooth staining or astringency and with effective tartar control by administering to a subject a stable dentifrice composition comprising a clinically effective amount of stannous fluoride and/or other stannous salts in combination with a fluoride ion source and a polymeric mineral surface active agent.
申请公布号 PL355965(A1) 申请公布日期 2004.05.31
申请号 PL20000355965 申请日期 2000.11.10
申请人 THE PROCTER & GAMBLE CO. 发明人 GLANDORF WILLIAM MICHAEL;BACCA LORI ANN;WHITE DONALD JAMES JR.;BUSSCHER HENK J.
分类号 A61K8/92;A61K8/19;A61K8/21;A61K8/24;A61K8/25;A61K8/29;A61K8/34;A61K8/36;A61K8/365;A61K8/40;A61K8/72;A61K8/73;A61K8/81;A61K8/90;A61Q11/00 主分类号 A61K8/92
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