发明名称 |
NOVEL DERIVATIVES OF 2,3-BENZODIAZEPIN, YHEIR PRODUCTION AND USE AS MEDICINES |
摘要 |
The invention concerns compounds of formula (I), in which R1, R2, R3 and R4 mean hydrogen or different substituents; X means hydrogen or halogen; Y means C1-6 alkoxy or X and Y together mean -O-(CH2)n-O-; n means 1, 2 or 3; and A together with nitrogen forms a saturated or unsaturated five-member heterocycle which can contain between 1 and 3 nitrogen atoms and/or an oxygen atom and/or one or two carbonyl groups. Owing to their non-competitive inhibiting of the AMPA receptors, these compounds can be used as medicaments for treating diseases of the central nervous system. |
申请公布号 |
PL187128(B1) |
申请公布日期 |
2004.05.31 |
申请号 |
PL19970328224 |
申请日期 |
1997.01.29 |
申请人 |
SCHERING AG |
发明人 |
CSUZDI ERNESE;HAMORI TAMAS;ABRAHAM GIZELLA;SOLYOM SANDOR;TARNAWA ISTVAN;BERZSENYI PAL;ANDRASI FERENC;LING ISTVAN;SIMAY ANTAL;GAL MELINDA;HORVATH KATALIN;SZENTKUTI ESZTER;SZOLLOSY MARTA;PALLAGI ISTVAN |
分类号 |
C07D243/02;A61K31/00;A61K31/55;A61K31/551;A61K31/675;A61P9/00;A61P9/10;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P43/00;C07D487/04;C07D491/04;C07D491/056;C07D491/14;C07D491/147;C07D498/04;C07D498/14;C07F9/6561 |
主分类号 |
C07D243/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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