QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTI-TUSSIVE AGENTS

摘要

In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn^- (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).