发明名称 AGENT FOR PREVENTING AND TREATING INTRAHEPATIC STONE, OR AGENT FOR PREVENTING RELAPSE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide an agent for preventing and treating intrahepatic stone, having excellent effects of enhancing the expression of human MDR3 on the pleural membrane of the bile duct, and accelerating the transportation of phospholipids to the bile duct, and to provide an agent for preventing the relapse thereof. SOLUTION: The medicinal composition containsα-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid (general name: bezafibrate) represented by the formula, or a pharmacologically acceptable salt thereof as an active ingredient. For example, when the bezafibrate of an active ingredient is orally administered, the dose per adult per day is 100-1,000 mg, preferably 400-600 mg, and the dose may be increased or decreased according to the symptom. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004149489(A) 申请公布日期 2004.05.27
申请号 JP20020319113 申请日期 2002.10.31
申请人 KISSEI PHARMACEUT CO LTD 发明人 SHODA JUNICHI;TANAKA NAOMI;INADA YOICHI;KUSAMA HIROSHI
分类号 A61P1/16;A61K31/195;C07C233/73;(IPC1-7):A61K31/195 主分类号 A61P1/16
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