摘要 |
<p>The present invention relates to a method of treatment or prevention of headache, migraine or cluster headaches, which method comprises co-administration of a therapeutically effective amount of the compound A = 1-[N 2 -[3, 5-Dibromo -N-[[4 -(3, 4-dihydro -2(1 H) -oxochinazolin-3 -yl)-1 piperidinyl] -carbonyl]-D -tyrosyl] -L-lysyl] -4-(4-pyridinyl) -piperazine [BIBN4096BS] or a physiologically acceptable salt thereof and a therapeutically effective amount of a second active antimigraine drug, particularly sumatriptan, zolmitriptan or dihydroergotamin or a physiologically acceptable salt thereof, as well as to the corresponding pharmaceutical compositions and the preparation thereof.</p> |