发明名称 USE OF BIBN4096 IN COMBINATION WITH OTHER ANTIMIGRAINE DRUGS FOR THE TREATMENT OF MIGRAINE.
摘要 <p>The present invention relates to a method of treatment or prevention of headache, migraine or cluster headaches, which method comprises co-administration of a therapeutically effective amount of the compound A = 1-[N 2 -[3, 5-Dibromo -N-[[4 -(3, 4-dihydro -2(1 H) -oxochinazolin-3 -yl)-1 piperidinyl] -carbonyl]-D -tyrosyl] -L-lysyl] -4-(4-pyridinyl) -piperazine [BIBN4096BS] or a physiologically acceptable salt thereof and a therapeutically effective amount of a second active antimigraine drug, particularly sumatriptan, zolmitriptan or dihydroergotamin or a physiologically acceptable salt thereof, as well as to the corresponding pharmaceutical compositions and the preparation thereof.</p>
申请公布号 MXPA04001364(A) 申请公布日期 2004.05.27
申请号 MX2004PA01364 申请日期 2002.08.10
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG. 发明人 WOLFGANG EBERLEIN
分类号 A61K45/00;A61K31/404;A61K31/4045;A61K31/4196;A61K31/422;A61K31/454;A61K31/48;A61K31/517;A61K31/56;A61P1/08;A61P1/14;A61P3/14;A61P25/00;A61P25/02;A61P25/06;A61P25/08;A61P25/26;A61P29/00;A61P37/08;A61P43/00;(IPC1-7):A61K31/404 主分类号 A61K45/00
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