ENGINEERED RNAi ADENOVIRUS SILENCING EXPRESSION (ERASE) OF DNA REPAIR PROTEINS
摘要
The present invention relates to compositions and methods for killing cancer cells and treating subjects having cancer comprising administering small inhibitory RNAs (siRNA) specific for DNA repair proteins in conjunction with administration of conventional DNA-damaging agents such as radiation and chemotherapeutic agents.
申请公布号
WO2004043406(A2)
申请公布日期
2004.05.27
申请号
WO2003US36367
申请日期
2003.11.12
申请人
THE JOHNS HOPKINS UNIVERSITY;DEWEESE, THEODORE, L.;COLLIS, SPENCER, J.;NELSON, WILLIAM, G.
发明人
DEWEESE, THEODORE, L.;COLLIS, SPENCER, J.;NELSON, WILLIAM, G.
