发明名称 COMPOSITION FOR TREATMENT OF MALE ERECTILE DYSFUNCTION CONTAINING PHENTOLAMINE AND ALPROSTADIL IN BUFFER CONTAINING L-ARGININE AND GLYCINE, WHICH HELPS CAUSE, PROMOTE AND MAINTAIN ERECTION AND INCREASES OR RECOVERS HUMAN SEXUAL REACTION WHEN INJECTED INTO CORPORA CAVERNOSA OF PENIS
摘要 PURPOSE: A composition for treatment of male erectile dysfunction containing phentolamine and alprostadil in a buffer containing L-arginine and glycine is provided. It helps cause, promote and maintain an erection and increases or recovers human sexual reaction when injected into the corpora cavernosa of the penis. CONSTITUTION: The composition for treatment of male erectile dysfunction contains phentolamine and alprostadil in a buffer containing a substrate for nitric oxide synthesis. The phentolamine is phentolamine mesylate, phentolamine hydrochloride or phentolamine salts which meet pharmaceutical standards. The composition contains phentolamine mesylate and alprostadil in a weight ratio of abut 5:0.005 and in a concentration of about 0 to 10mg/ml and about 0 to 40mg/ml respectively. The substrate for nitric oxide synthesis is a mixture of L-arginine and glycine.
申请公布号 KR20040043996(A) 申请公布日期 2004.05.27
申请号 KR20020072485 申请日期 2002.11.20
申请人 ZONAGEN INC. 发明人 PODOLSKI JOSEPH S.
分类号 A61K31/5575;(IPC1-7):A61K31/557 主分类号 A61K31/5575
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