| 发明名称 |
2-PYRIDONE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE |
| 摘要 |
<p>There are provided novel compounds of formula (I) wherein R¿1<, R¿4?, R¿5?, G¿1?, G¿2?, X, L, Y¿1?, Y¿2? and n are as defined in the Specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of neutrophil elastase.</p> |
| 申请公布号 |
WO2004043924(A1) |
申请公布日期 |
2004.05.27 |
| 申请号 |
WO2003SE01739 |
申请日期 |
2003.11.11 |
| 申请人 |
ASTRAZENECA AB;BLADH, HAAKAN;KLINGSTEDT, TOMAS;LARSSON, JOAKIM;LAWITZ, KAROLINA;LEPISTOE, MATTI;LOENN, HANS;NIKITIDIS, GRIGORIOS |
发明人 |
BLADH, HAAKAN;KLINGSTEDT, TOMAS;LARSSON, JOAKIM;LAWITZ, KAROLINA;LEPISTOE, MATTI;LOENN, HANS;NIKITIDIS, GRIGORIOS |
| 分类号 |
A61K31/4412;A61K31/505;A61P29/00;C07D;C07D211/86;C07D213/64;C07D213/82;C07D239/54;C07D239/557;C07D241/24;C07D413/12;(IPC1-7):C07D211/86;A61K31/441;C07D239/22 |
主分类号 |
A61K31/4412 |
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