METHOD FOR THE PREPARATION OF PACLITAXEL SOLID DISPERSION BY USING THE SUPERCRITICAL FLUID PROCESS AND PACLITAXEL SOLID DISPERSION PREPARED THEREBY

摘要

The present invention relates to a method for the preparation of paclitaxel solid dispersion by using the supercritical fluid process and paclitaxel solid dispersion prepared thereby, the paclitaxel solid dispersion being highly homogeneous and showing an improved solubility, thereby being effectively used for the preparation of paclitaxel injection and oral preparation having a high bioavailability.